The loss left Lille in tenth place forward of internet hosting German Bundesliga highflyers Wolfsburg of their Champions League opener subsequent week.
It additionally ended their nice 10-month run with out a loss on the highway.
“It’s an unacceptable defeat,” Lille central defender Jose Fonte informed Prime Video. “We should do higher, present extra willpower.”
Moffi, 22, offered the help for Armand Lauriente to present the hosts an early edge.
Turkish veteran Burak Yilmaz had Lille again stage from the penalty spot on 25 minutes after minor contact with Julien Laporte.
With the sport heading for a draw Vincent Le Goff picked out the tireless Moffi who escaped his two markers to safe the winner in rhe 86th minute.
On Saturday Paris Saint-Germain face promoted Clermont disadvantaged of Lionel Messi, Angel Di Maria and Neymar after the South American World Cup qualifiers on Thursday.
PSG boss Mauricio Pochettino is ready on the health of Kylian Mbappe, who left the France camp with a calf damage he suffered of their first qualifier of the worldwide break towards Bosnia and Herzegovina.
Saturday’s different sport sees Marseille at Monaco.